Activation of human lymphocytes in vitro by membrane-damaging toxins from Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
In vitro protection of human lymphocytes from toxic effects of chlorpyrifos by selenium-enriched medicines
Objective(s): Chlorpyrifos (CP) is a broad-spectrum organophosphorus pesticide used extensively in agricultural and domestic pest control, accounting for 50% of the global insecticidal use. In the present study, protective effects of two selenium-enriched strong antioxidative medicines IMOD and Angipars were examined in human lymphocytes treated with CP in vitro. Materials and Methods: Isolate...
متن کاملStaphylococcus aureus toxins.
Staphylococcus aureus is a dangerous pathogen that causes a variety of severe diseases. The virulence of S. aureus is defined by a large repertoire of virulence factors, among which secreted toxins play a preeminent role. Many S. aureus toxins damage biological membranes, leading to cell death. In particular, S. aureus produces potent hemolysins and leukotoxins. Among the latter, some were rece...
متن کاملNonenteric toxins of Staphylococcus aureus.
INTRODUCTION ..... .. 320 STAPHYLOCOCCAL SCALDED SKIN SYNDROME 322 Experimental Model 324 Association of the Staphylococcal Scalded Skin Syndrome with Exfoliative Toxin ................. ... .324 EXFOLIATIVE TOXIN 325 Production 325 Isolation and Purification ... 326 Properties .. 326 Genetic Regulation ......................... ..... 331 ALPHA-TOXIN ......................... ...... 337 Overvie...
متن کاملExfoliative Toxins of Staphylococcus aureus
Staphylococcus aureus is an important pathogen of humans and livestock. It causes a diverse array of diseases, ranging from relatively harmless localized skin infections to life-threatening systemic conditions. Among multiple virulence factors, staphylococci secrete several exotoxins directly associated with particular disease symptoms. These include toxic shock syndrome toxin 1 (TSST-1), enter...
متن کاملImmunogenicity of toxins during Staphylococcus aureus infection.
BACKGROUND Toxins are important Staphylococcus aureus virulence factors, but little is known about their immunogenicity during infection. Here, additional insight is generated. METHODS Serum samples from 206 S. aureus-infected patients and 201 hospital-admitted control subjects were analyzed for immunoglobulin (Ig) G binding to 20 toxins, using flow-cytometry based technology. Antibody levels...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1981
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.31.3.952-956.1981